Cellular Nanomedicine & Chemical Biology Lab
School of Biological Sciences,
UM-DAE Centre for Excellence in Basic Sciences, Mumbai
Dr. Manu Lopus is a Reader in Biology at the School of Biological Sciences, UM-DAE Centre for Excellence in Basic Sciences, Mumbai. Dr. Lopus earned his PhD in Biotechnology from Indian Institute of Technology Bombay where he studied the mechanistic details of tubulin-targeted anticancer molecules. As an NIH Postdoctoral Fellow at the University of California Santa Barbara, his studies shed light on the regulation of microtubule dynamics by plus-end-interacting proteins and potent anticancer drugs. His major research areas are mechanistic and efficacy studies of design-optimized nanotherapeutics, and molecular mechanisms involved in non-apoptotic cell death. Dr. Lopus is an Editorial Board Member of Oncology Letters and Molecular Medicine Reports, an elected Fellow of the Royal Society of Biology (2021), the Royal Society of Chemistry (2022), the Maharashtra Academy of Sciences (2022), and a Life Member of the National Academy of Sciences, India (since 2017). He has been actively involved in teaching undergraduate and postgraduate courses, guiding PhD students and postdoctoral fellows, communicating science through popular articles and lectures, and organizing scientific seminars and colloquia. He can be reached at manu.lopus@cbs.ac.in
​
Principal Investigator
Manu Lopus
PhD Students
Ms. Kimaya Meher
Kimaya obtained her MSc in Biotechnology from St. Xavier's College, Mumbai. Area of Research: Mechanisms of action of natural products in cancer cells, Green-nanotechnology, Nanoforumlation of anticancer drugs
Ms. G Radha
Radha obtained her MSc in Microbiology from St. Xavier's College, Mumbai.
Area of Research: Cell death mechanisms regulated by microtubules. Non-apoptotic cell death pathways
Ms. Bhavisha Patel
Bhavisha obtained her MSc in Life Sciences from the University of Mumbai.
Area of Research: Investigation of the nature of cell death induced by surface-functionalized metal nanoparticles
Mr. Gandhar Pusalkar
Gandhar obtained his MSc in Biotechnology from the Hislop College, Nagpur University. Area of Research: Metabolic and structural alterations induced by therapeutic nanoparticles in cancer cells
Ms. Garima Gehlot
Garima Obtained BSc in Life Sciences from Delhi University and MSc in Biotechnology from Siksha O' Anusandhan University, Odisha. Area of Research: Development of synergistic anticancer drug combinations and their nanoformulations
PhD Students co-guided
Dr. Shruti Gamya Dash
Thesis: Preclinical Evaluation of Potential Synergistic Effect of Noscapinoids and Taxotere for Breast Cancer Therapy (Co-guided with Prof. Pradeep Naik, Sambalpur University, Odisha). Status: PhD degree granted
Dr. Pratyush Pragyandipta
Thesis: Development of Noscapine Congeners for the Treatment of Breast Cancer. (Co-guided with Prof. Pradeep Naik, Sambalpur University, Odisha). Status: PhD degree granted
Mr. Rajesh Kumar Meher
Thesis: Rational Design of Novel Tubulin-binding Anticancer Agents Based on Chemotherapeutic Evaluation of Noscapinoids, Their Chemical Synthesis and Experimental Validation (Co-guided with Prof. Pradeep Naik, Sambalpur University, Odisha. Status: Thesis submitted
Postdoctoral Fellows trained in the Lab
Dr. Grace Nirmala
Dr. Madhura Pradhan
Dr. Sanith C.
